Wednesday, September 27, 2006

MS Drugs Unsafe in Pregnancy?

Many people have queried: "Are current MS immunomodulating and other drug therapies safe during pregnancy?"

In many cases, either the pharmaceutical companies have made no statement or tested their safety during pregnancy, or "the jury may still be out." However, in some cases, the answer is a definitive "NO."

Here's a list:

IMMUNOMODULATORS

AVONEX (Interferon beta-1a) - contraindicated in pregnancy
BETASERON (Interferon beta-1b) - contraindicated in pregnancy
COPAXONE (Glatiramer Acetate) - usually safe but benefits must outweigh the risks
REBIF (Interferon beta-1a) - safety for use during pregnancy has not been established
TYSABRI (Natalizumab) - safety for use during pregnancy has not been established

IMMUNOSUPRESSANTS

NOVANTRONE (Mitoxantrone) - unsafe in pregnancy
CYTOXAN or NEOSAR (Cyclophosphamide) - unsafe in pregnancy

CORTICOSTEROIDS

SOLU-MEDROL, DEPO-MEDROL (methylprednisolone) - safety for use during pregnancy has not been established

FOR DETAILED INFORMATION AND GUIDANCE, PLEASE CONSULT YOUR PHYSICIANS.