Monday, October 30, 2006

Commentary: Delaying technology is deadly

from The Washington Times

By Paul Driessen

In sub-Saharan Africa and poor areas of Asia and Latin America, diarrhea isn't just a source of mild discomfort and juvenile bathroom humor. Because of unsanitary conditions, contaminated water and food infected by bacteria in feces used for fertilizer, people in those regions endure 4 billion episodes of severe diarrhea a year. Up to 2 million die annually.

Among children in the United States, acute diarrhea accounts for more than 1.5 million outpatient visits, 200,000 hospitalizations, and 300 deaths a year. It imposes a multibillion-dollar burden on the U.S. health-care system.

But miracles of modern medical and agricultural science offer hope. For years, glucose-based rehydration solutions (similar to Pedialyte) were used to treat diarrhea. They saved countless lives, by replacing lost salts, sugars and bodily fluids. However, even with the successful health outcomes, these solutions did not reduce the incidence or severity of childhood diarrhea.

Now Ventria Bioscience has developed an advanced solution that augments standard rehydration solutions, by adding protective human proteins (lactoferrin and lysozyme) found in all human saliva and breast milk.

A recent child health study demonstrated the proteins cut the average duration of children's diarrhea by 30 percent (1-1/2 days), and patients were half as likely to get diarrhea again during the next 12 months. Equally important, Ventria produces the proteins in a special variety of rice, which makes its rehydration solution affordable, even for people in poor countries.

Ventria achieved its remarkable breakthrough by altering rice DNA and using rice plants as factories that utilize the sun, soil and water as raw materials to produce the proteins. The company extracts the proteins and adds them to rehydration solutions. Its success could convert one of the world's most essential foods into a valuable lifesaver.

In another achievement, SemBioSys Genetics created genetically engineered safflowers that produce insulin at commercial levels: An acre of safflower can produce a kilogram of insulin, enough for 2,500 patients. Fewer than 16,000 acres -- about 0.2 percent of what Iowa farmers devote to corn -- would cover projected 2010 world demand for insulin. With diabetes on the rise in India and elsewhere, this advance could be vital.

Syngenta is working on plant-based antibodies that fight infections and skin disease. Other scientists are enhancing plants to produce vaccines, hormones and enzymes that can treat HIV, cancer, heart and kidney disease, spinal cord injuries, multiple sclerosis, cystic fibrosis, hepatitis, anthrax, West Nile virus and arthritis.

It costs around $1,000 to produce 1 gram (0.035 ounce) of protein from animal cells, making many such vaccines prohibitively costly for even the wealthiest countries, and completely out of reach for destitute countries. Producing the same amount from gene-altered plants would cost less than $20 -- and that means pharmaceutical companies could give higher priority to finding cures for rare and "orphan" diseases across the globe.

But amazingly, instead of applauding these lifesaving innovations, critics attack them. Luddite radicals like the Center for Food Safety, Union of Concerned Scientists and Greenpeace assert this "Frankenstein" technology tampers with nature and could "contaminate" other crops. These groups are well funded by organic food interests and others who profit by attempting to scare the public. The European Union and organic food industries demand stringent, costly, unnecessary regulations that impose unconscionable delays and result in death for some of the world's most needy children.

Breeders have been improving plants for millennia, using various genetic technologies. Plant biotechnology is simply a refinement of the earlier, cruder techniques. Today's researchers employ genetic technologies that are far more careful and precise -- and management practices that maintain closed production systems and virtually eliminate any risks of accidental cross-pollination and gene migration.

But none of this makes any difference to "anti-humanists who put unfounded fear-mongering ahead of the world's children," says Greenpeace co-founder Patrick Moore. Healthy, well-fed, safe from diseases that kill millions in other countries, with access to abundant clean water and electricity -- they obsess about purely speculative risks from technologies that could improve and save countless lives.

In so doing, they perpetuate disease risks for countless human beings. They throw roadblocks in the path of scientific and technological progress that so far has eluded the world's poor, even as it improved our own health, nutrition, living standards and lifespans.

My personal experience with polio (luckily after receiving two Salk inoculations) made me eternally grateful that these "ethicists" weren't around 50 years ago to stymie research and field trials of that vaccine. My generation can also count its blessings for treatments, antibiotics and other vaccines that have saved many of us and our children.

It is now the responsibility of our generation to protect children, the poor and future generations from mean-spirited Luddite groups paid to undermine our humanity and technological progress. It is time for legislators, regulators, judges and people of conscience to say "enough."

The world needs these miraculous technologies -- today. And those who support radical anti-biotech organizations need to understand that, by blocking health-care innovations, they are perpetuating misery, disease and premature death in countries the world over. That is simply immoral.

Paul Driessen is senior policy adviser for the Congress of Racial Equality and Committee For A Constructive Tomorrow, and author of "Eco-Imperialism: Green power — Black death" (www.Eco-Imperialism.com).


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