Tuesday, December 19, 2006

Multiple Sclerosis Is the Most Common Cause of Neurological Disability in Young Adults in the UK





December 19, 2006 10:30 AM Eastern Time

DUBLIN, Ireland--(BUSINESS WIRE)--Research and Markets (http://www.researchandmarkets.com/reports/c47292) has announced the addition of Espicom Business Intelligence’s CNS Drug Discoveries: Multiple Sclerosis Chapter to their offering.

The incidence of multiple sclerosis varies throughout the world, although there is a significantly higher incidence of the disease found in the Northern Hemisphere. Find out more in this chapter of CNS Drug Discoveries.

It is estimated that over 350,000 Americans (approximately 1 in 1,000 aged over 30 years) live with multiple sclerosis (MS) and approximately 3 million live with it worldwide. However, the prevalence may be higher because of the uncertainty in diagnosing the condition. Women are twice as susceptible as men and it is more common in people in northern latitudes over the age of 18 years. In addition, siblings of an individual with multiple sclerosis have a higher chance of developing the disease.

The incidence of multiple sclerosis varies throughout the world, although there is a significantly higher incidence of the disease found in the northern hemisphere. Multiple sclerosis is the most common cause of neurological disability in young adults in the UK.

It is variable in presentation and progression. Although there is no cure, there are many symptomatic treatments available. However, many patients do not respond to currently available products (30%) and the more chronic forms (secondary-progressive MS) are poorly treated with existing therapies.

Global multiple sclerosis market

The MS market is estimated to be worth US$4.9 billion in 2006 with a growth rate of 8.9% year-on-year. It is the fifth largest segment of the CNS market and has attracted considerable R&D investment from big pharma, biotechnology companies and specialty pharma. The market is currently driven by the use of six disease-modifying agents: Avonex (Biogen Idec), Betaseron/Betaferon (Schering AG), Copaxone (Teva), Novatrone (Schering AG), Rebif (Serono/Pfizer) and Tysabri (Biogen Idec/Elan).

Sales growth will be driven by current drugs gaining broader indications, MS medicine being prescribed earlier in treatment in clinically-defined multiple sclerosis patients and the longer-term use of combination therapies as more classes of drug become available.

Key questions answered in this chapter include:

-What are the 5 leading products in the US, Europe and Japan?

-What will the shape of the market be in 2012?

-How will Biogen Idec defend its market leading position from Serono, Schering AG and Teva?

-What role will combination therapies play?

-What opportunities are there in the treatment of primary-progressive multiple sclerosis?

-What are the prospects for drugs in development such as Campath, Mylinax, and laquinimod?

Content Outline:

MULTIPLE SCLEROSIS

EXECUTIVE SUMMARY

THE FACTS

PATIENT STATISTICS

PATIENT MODEL

DRUG GROWTH DRIVERS

DRUG GROWTH RISKS/DAMPENERS

GLOBAL MS MARKET

GLOBAL SALES SPLIT

CURRENT TREATMENTS

ANALYSIS OF LEADING BRANDS

Disease-modifying agents

GLOBAL SALES FORECASTS OF CURRENT TREATMENTS 2005–2012

NEW DRUGS IN R&D

ANALYSIS OF PHASE III DRUGS

MS Symptoms

GLOBAL SALES FORECASTS OF PHASE III MS DRUGS 2006–2012

ANALYSIS OF PHASE II DRUGS

Disease-modifying agents

Vaccines

GLOBAL SALES FORECASTS OF PHASE II MS DRUGS 2006 – 2012

COMPETITOR RATIO ANALYSIS - PRODUCTS

COMPETITOR RATIO ANALYSIS - COMPANIES

DISCONTINUATION OF DRUGS

MS APPENDIX 1

MS APPENDIX 2

MS APPENDIX 3

MS APPENDIX 4

MS APPENDIX 5

Ms APPENDIX 6

MS GLOSSARY

MS REFERENCES

ACRONYMNS

For more information visit http://www.researchandmarkets.com/reports/c47292

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