Glenmark purchases rights to two therapeutic antibodies from Chromos

Mumbai, India and Burnaby, British Columbia, Canada July 19, 2007 - Glenmark Pharmaceuticals S.A., the wholly-owned Swiss subsidiary of Glenmark Pharmaceuticals Ltd. (Glenmark) and Chromos Molecular Systems Inc. (Chromos) (TSX:CHR) of British Columbia, Canada, announced today that they have completed the purchase by Glenmark of Chromos’ two New Biological Entities (NBE’s) CHR-1103 and CHR-1201. The two NBE’s are humanized monoclonal therapeutic antibodies.

Under the terms of the transaction agreements between Glenmark and Chromos, Glenmark has purchased all rights to the two products as well as rights to use Chromos’ proprietary ACE System technology for cell line development for use with respect to CHR-1103 and CHR- 1201. Glenmark holds the worldwide rights for further development, registration and
commercialization of these products. Financial terms of the transaction are not to be released.

CHR-1103 and CHR-1201 are part of a validated class of drugs known as SAMI’s (selective adhesion molecule inhibitors) that includes such drugs as ReoPro (Centocor/Lilly), Raptiva (Genentech/Xoma) and Tysabri (Biogen/Elan). CHR-1103 is a broad anti inflammatory agent with a novel mechanism of action, being developed initially to treat acute multiple sclerosis, for which there is no treatment approved at present. Glenmark plans to initiate Phase I clinical trials in 2008 and complete Phase 1 on CHR-1103 by March 2009. CHR-1201 is an anti-thrombolytic humanized monoclonal antibody, which Glenmark plans to develop initially to treat acute stroke. Glenmark plans to start Phase I on CHR-1201 by March 2009.

On this occasion, Glenn Saldanha, Managing Director and CEO of Glenmark Pharmaceuticals Ltd., stated, “This is a very important addition to our pipeline of Novel Biological Entities. These two NBE’s would help accelerate our pipeline in the biologics space.” Michael Buschle, President – Biologics at Glenmark Switzerland said, “These therapies hold a lot of promise in areas of high unmet medical need and also fit very well within our areas of focus. We are delighted with the addition of these two highly exciting molecules to our rapidly expanding pipeline”.

"We share Glenmark's enthusiasm for these antibodies, and are pleased that these therapies will be moved forward with the support of Glenmark's outstanding infrastructure and personnel" said Alistair Duncan, President and Chief Executive Officer of Chromos. As part of Chromos’ on-going restructuring proceedings under the Bankruptcy and Insolvency Act, the Supreme Court of British Columbia in Bankruptcy has approved this transaction. The upfront proceeds from this purchase transaction will be used to repay Chromos’ secured creditors.

About Glenmark

Glenmark Pharmaceuticals Ltd. is a research-led, global, fully integrated pharmaceutical company headquartered in Mumbai, India. The Company is a leader in India in the discovery of new molecules and is focused in the areas of inflammation [Asthma/COPD, etc] and metabolic disorders [Diabetes, Obesity, etc]. The Company has generic formulation and API business interests in over 80 countries across the world including the highly regulated markets of USA and Europe. The formulation
business spans several product segments such as Dermatology, Internal Medicine, Paediatrics, Gynaecology, ENT, Diabetes and Oncology. Glenmark’s first Asthma/COPD molecule, Oglemilast [GRC 3886], was licensed out to Forest Laboratories and Teijin Pharma Limited for the North American and Japanese markets, respectively, in two landmark deals. Oglemilast is presently undergoing Phase II clinical trials in the US. The Company’s second lead GRC 8200, a DPP-IV inhibitor for Type II Diabetes was out-licensed to Merck KGaA, Germany for the North American, European and Japanese markets. A third molecule targeting pain, GRC 6211, is undergoing Phase II clinical trials in Europe. Glenmark has three other programmes across obesity, inflammation and pain management at the pre-clinical stages; all of which should enter the clinics in H1 FY 2008. [www.glenmarkpharma.com]

For Further Information, Please Contact:
Vasudha Jha,
Tel: +91 22 6758 9919 / +919833822406
Email: media@glenmarkpharma.com

About Chromos

Chromos is a biopharmaceutical company focused on the development and commercialization of its proprietary ACE System technology that is used to engineer production quality cell lines to manufacture biopharmaceutical products including monoclonal antibodies and the development of human therapeutic products. As part of its ongoing restructuring efforts, on April 12, 2007 Chromos filed a Notice of Intention to Make a Proposal to its creditors under the Bankruptcy and Insolvency Act.

For more information visit our website at www.chromos.com.

Risks and Uncertainties

Certain of the statements contained in this press release are forward-looking statements which involve known and unknown risks, uncertainties and other factors which may cause the actual results, performance or achievements of Chromos, or industry results, to be materially different from any future results, performance or achievements expressed or implied by such forward-looking statements.

To the extent possible, management implements strategies to reduce or mitigate the risks and uncertainties associated with Chromos’ operations. Operating risks include (i) the continued availability of capital to finance Chromos’ activities; (ii) Chromos’ limited cash position, (iii) the ability to successfully obtain proof of the effectiveness of Chromos’ technology (iv) the ability to complete and maintain corporate alliances relating to the development and commercialization of Chromos’ technology; (v) the ability to obtain and enforce patent and other intellectual property protection for Chromos’ technology; (vi) market acceptance of Chromos’ technology; (vii) the competitive environment and impact of technological change; (viii) Chromos’ ability to attract and retain employees to carry out its business plans; (ix) the timely development and commercialization of any technology or products that are contingent on the completion and maintenance of corporate alliances with third parties (x) the demand for repayment of the outstanding Notes by the Noteholders; (xi) approval of any proposal to creditors made under the Bankruptcy and Insolvency Act; and (xii) re-emergence from its reorganization proceedings. Further details on Chromos’ operating risks can be found in its most recently filed Annual Information Form and in its Quarterly and Annual Reports to Shareholders.

For Further Information, Please Contact:

Jeff Charpentier, CA
Vice President Finance and CFO
604-415-7132
email: jcharpentier@chromos.com

Chromos announces demand for bridge loan repayment

BURNABY, BC, April 3 /CNW/ - Chromos Molecular Systems Inc. ("Chromos") (TSX:CHR) announced today that the holders of the convertible, secured bridge loan have demanded repayment of the principal and interest, totaling approximately $2,242,000, by April 4, 2007. Chromos does not currently have sufficient funds to satisfy this demand.

The Company is attempting to arrange financing to satisfy this demand for repayment and exploring other strategic alternatives. There can be no assurance that additional financing will be available at all or on acceptable terms to permit Chromos' current operations to continue. If Chromos is unsuccessful in raising sufficient financing it will be required to scale back or terminate certain or all of its operations.

About Chromos

Chromos is a biopharmaceutical company with two drug development programs focused on inflammatory diseases and thrombotic disorders. The Company's lead product, CHR-1103, is a humanized monoclonal antibody being developed as an
acute treatment for relapses associated with multiple sclerosis (MS). Chromos generates revenue from its proprietary ACE System technology to engineer production quality cell lines to manufacture biopharmaceutical products
including monoclonal antibodies. For more information, please visit our website at www.chromos.com.

Risks and Uncertainties

Certain of the statements contained in this press release are forward-looking statements which involve known and unknown risks, uncertainties and other factors which may cause the actual results, performance or achievements of Chromos (the "Company"), or industry results, to be materially different from any future results, performance or achievements expressed or implied by such forward-looking statements.

To the extent possible, management implements strategies to reduce or mitigate the risks and uncertainties associated with the Company's operations. Operating risks include (i) the continued availability of capital to finance the Company's activities; (ii) the Company's limited cash position, (iii) the ability to successfully obtain proof of the effectiveness of the Company's technology (iv) the ability to complete and maintain corporate alliances relating to the development and commercialization of the Company's technology; (v) the ability to obtain and enforce patent and other intellectual property
protection for the Company's technology; (vi) market acceptance of the Company's technology; (vii) the competitive environment and impact of technological change; (viii) the Company's ability to attract and retain employees to carry out its business plans; (ix) the timely development and commercialization of any technology or products that are contingent on the
completion and maintenance of corporate alliances with third parties; (*) the demand for repayment of the outstanding Notes by the Noteholders and (xi) regulatory approval of the conversion of the outstanding Notes. Further details on Chromos' operating risks can be found in the Company's Quarterly and Annual Reports to Shareholders.



For further information: Jeff Charpentier, CA, Vice President Finance and CFO, (604) 415-7132, email: jcharpentier@chromos.com

Chromos Announces Corporate Developments

For Immediate Release: March 19, 2007

Burnaby, British Columbia, Canada, Chromos Molecular Systems Inc. (“Chromos”) (TSX:CHR) announced today corporate developments related to its lead product candidate, CHR-1103, its convertible bridge loan and its Board of Directors.

Proposed CHR-1103 Collaboration
Chromos announced a non-binding term sheet with a U.S.-based biotechnology company under which it will enter into a collaboration agreement to co-develop its lead product, CHR-1103. Under the proposed collaboration, the U.S. biotechnology company will pay to Chromos US$3,000,000 upon execution of definitive agreements as well as additional future milestone payments. The partner company will assume the funding for a significant majority of the development expenses for the CHR-1103 program. Based on this expense funding ratio, the parties will share proportionately revenues related to the commercialization of CHR-1103, including all clinical indications. No other financial terms were disclosed. The transaction is subject to completion of final due diligence and execution of definitive agreements, which is expected to take place in April 2007.

“The formation of this collaboration will provide Chromos with a co-development partner for CHR-1103 that is led by a seasoned leadership team with the financial resources to assist driving this product through clinical development,” said Alistair Duncan, President and CEO of Chromos. “This collaboration will also allow us to mitigate risk in the development of our first therapeutic product candidate and to maintain our focus on continuing to grow our cell line engineering business utilizing our proprietary ACE System.”

CHR-1103 is a humanized monoclonal antibody directed against VLA-2, an integrin involved in maintenance of inflammation. In preclinical studies, it has been demonstrated that anti-VLA2 therapy reduces clinical signs of inflammation in animal models of multiple sclerosis (MS), inflammatory bowel disease and arthritis. The initial focus CHR-1103 is the acute treatment of relapse in MS. It is anticipated that an Investigational New Drug (IND) application for CHR-1103 will be filed at the beginning of 2008.

Amendments to the Terms of the Convertible Bridge Loan

Chromos has increased the convertible bridge loan financing arrangement that was previously announced on October 20, 2006 by $150,000 to $2,150,000. The additional proceeds of the loan will be used to fund operations of Chromos as it seeks to complete the proposed CHR-1103 collaboration and to raise additional financing.

In addition, for the promissory notes issued under the bridge loan, effective anytime after March 29, 2007 the note holders may demand repayment of the notes together with any accrued interest on one days’ notice. This is a reduction in the notice period from the previous 10 days notice. In addition, if Chromos does not provide, on or before March 21, 2007, evidence to the satisfaction of the note holders that an equity financing is being arranged for a specified minimum size with a portion of the proceeds being used to repay the notes, then the notes will become immediately due and payable. The Company is actively pursuing an equity financing that is intended to provide the required evidence. The note holders, who are also significant common shareholders of the Chromos, have assured the Company of their endorsement for both a successful equity financing outcome and the proposed CHR-1103 collaboration. The conversion feature for the bridge loan has also been amended so that it is at the option of the note holders.

Chromos’ current funds on hand, anticipated revenues from existing contractual agreements and the $150,000 of additional funds available from the bridge loan financing are expected to be sufficient to fund its operations until approximately the end of April of 2007. This assumes that in the interim the note holders of the bridge loan have not otherwise demanded repayment, in accordance with their rights as noted above, in which case Chromos would have insufficient funds to satisfy repayment requirements. There can be no assurance that Chromos will be able to complete the proposed CHR-1103 collaboration transaction or that additional financing will be available at all or on acceptable terms to permit Chromos’ current operations to continue. If Chromos is unsuccessful in raising additional financing it may be required to scale back or terminate certain or all of its operations.

Director Resignation
Chromos also announced that Mr. David Barr has resigned from its Board of Directors. Mr. Barr is CFO and Investment Manager of PenderFund Capital Management Ltd. which manages funds that are holders of a portion of the convertible, secured promissory notes. Mr. Barr indicated that he tendered his resignation as a director to avoid any potential conflict of interest created by PenderFund’s ownership position of the convertible bridge loan referred to above.

This resignation brings the number of directors on the Board to four.

About Chromos
Chromos is a biopharmaceutical company with two drug development programs focused on inflammatory diseases and thrombotic disorders. The Company's lead product, CHR-1103, is a humanized monoclonal antibody being developed as an acute treatment for relapses associated with multiple sclerosis (MS). Chromos generates revenue from its proprietary ACE System technology to engineer production quality cell lines to manufacture biopharmaceutical products including monoclonal antibodies. For more information, please visit our website at www.chromos.com.

Risks and Uncertainties
Certain of the statements contained in this press release are forward-looking statements which involve known and unknown risks, uncertainties and other factors which may cause the actual results, performance or achievements of Chromos (the “Company”), or industry results, to be materially different from any future results, performance or achievements expressed or implied by such forward-looking statements.

To the extent possible, management implements strategies to reduce or mitigate the risks and uncertainties associated with the Company’s operations. Operating risks include (i) the continued availability of capital to finance the Company’s activities; (ii) the Company’s limited cash position, (iii) the ability to successfully obtain proof of the effectiveness of the Company’s technology (iv) the ability to complete and maintain corporate alliances, including the proposed CHR-1103 collaboration, relating to the development and commercialization of the Company’s technology; (v) the ability to obtain and enforce patent and other intellectual property protection for the Company’s technology; (vi) market acceptance of the Company’s technology; (vii) the competitive environment and impact of technological change; (viii) the Company’s ability to attract and retain employees to carry out its business plans; (ix) the timely development and commercialization of any technology or products that are contingent on the completion and maintenance of corporate alliances with third parties; (x) the demand for repayment of the outstanding notes by the note holders and (xi) regulatory approval of the conversion of the outstanding notes. Further details on Chromos’ operating risks can be found in the Company’s Quarterly and Annual Reports to Shareholders.

For Further Information:
Jeff Charpentier, CA
Vice President Finance and CFO
604-415-7132
email: jcharpentier@chromos.com